The Kiwi heavyweight outpointed his British rival in a close match which saw the pair slug it out through 12 rounds. Parker, 29, dropped the Brit twice over the match and left him held up by the ropes on another occasion but Chisora, 37, showed off his incredible stamina and recovery to hear the final bell.
Chisora was ultimately forced to accept his fate after the judges returned scores of 115-110, 115-111 and 114-112 in favour of the New Zealand boxer.
In a victory interview, Parker said: “Derek always comes for war, he was one tough guy and never stopped coming forward until the end
“I felt a lot stronger. It was important to start strong and not be negative from the beginning.
“You can see there are improvements to be made.
Parker continued: “Derek Chisora is a credit to the sport of boxing.
“The crowd went mental when he walked out. They just want to support him.”
The match last night was the second time the rivals had faced off, after Chisora was dealt a devastating defeat in their match seven months ago, in which Parker won out after a split-decision.
Saturday’s match saw the Brit come out swinging in the opening round, leaving Parker on the canvas before falling off pace as the match went on.
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The loss for Chisora now marks his 12th defeat in a 44-fight career.
Asked if he would like to see Chisora retire from boxing, Parker replied: “Personally I’d like to see him walk away.
“He has given boxing everything he has. The atmosphere is amazing when he fights. I’d love to see him walk away but that’s his decision.”